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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: DGKH All Species: 29.39
Human Site: S958 Identified Species: 80.83
UniProt: Q86XP1 Number Species: 8
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens Q86XP1 NP_690874.2 1220 134866 S958 A F E S T L K S W E D K Q K C
Chimpanzee Pan troglodytes XP_001151474 1220 134870 S958 A F E S T L K S W E D K Q K C
Rhesus Macaque Macaca mulatta XP_001114920 1167 129871 S904 A F E S T L K S W E D K Q K C
Dog Lupus familis XP_534133 1182 132580 S920 A F E S T L K S W E D K Q K C
Cat Felis silvestris
Mouse Mus musculus
Rat Rattus norvegicus
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001507672 1254 138458 S991 A F E N T L K S W E D K Q K Y
Chicken Gallus gallus XP_001232791 1333 149344 S1070 A F E N T L K S W E D K Q K Y
Frog Xenopus laevis
Zebra Danio Brachydanio rerio NP_001108193 586 65385 Q361 T K I L N S D Q H S V V I S S
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster A8JQ65 1895 211641 S1625 S L E L S L K S W Q E K Q R Q
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_001202627 1158 127377 S884 H F E S T L K S W T E R R K I
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 99.5 62.2 90.7 N.A. N.A. N.A. N.A. 82.3 76.8 N.A. 39 N.A. 34.9 N.A. N.A. 51.5
Protein Similarity: 100 99.8 73.4 92.8 N.A. N.A. N.A. N.A. 88.1 82.9 N.A. 43.2 N.A. 46.5 N.A. N.A. 64.1
P-Site Identity: 100 100 100 100 N.A. N.A. N.A. N.A. 86.6 86.6 N.A. 0 N.A. 46.6 N.A. N.A. 60
P-Site Similarity: 100 100 100 100 N.A. N.A. N.A. N.A. 93.3 93.3 N.A. 0 N.A. 80 N.A. N.A. 80
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 67 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 45 % C
% Asp: 0 0 0 0 0 0 12 0 0 0 67 0 0 0 0 % D
% Glu: 0 0 89 0 0 0 0 0 0 67 23 0 0 0 0 % E
% Phe: 0 78 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % G
% His: 12 0 0 0 0 0 0 0 12 0 0 0 0 0 0 % H
% Ile: 0 0 12 0 0 0 0 0 0 0 0 0 12 0 12 % I
% Lys: 0 12 0 0 0 0 89 0 0 0 0 78 0 78 0 % K
% Leu: 0 12 0 23 0 89 0 0 0 0 0 0 0 0 0 % L
% Met: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % M
% Asn: 0 0 0 23 12 0 0 0 0 0 0 0 0 0 0 % N
% Pro: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % P
% Gln: 0 0 0 0 0 0 0 12 0 12 0 0 78 0 12 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 0 12 12 12 0 % R
% Ser: 12 0 0 56 12 12 0 89 0 12 0 0 0 12 12 % S
% Thr: 12 0 0 0 78 0 0 0 0 12 0 0 0 0 0 % T
% Val: 0 0 0 0 0 0 0 0 0 0 12 12 0 0 0 % V
% Trp: 0 0 0 0 0 0 0 0 89 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 23 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _